Make sure you check out who is active and who isn’t before the NFL Week 13 early afternoon slate of games while you set your lineups:
James Conner, RB, Pittsburgh Steelers (shoulder) – Conner participated in a limited practice on Thursday and is marked as doubtful for the Steelers in Week 13. He has not been at full strength since Week 8 against the Dolphins with a shoulder injury. This will mean more work for Benny Snell, Jaylen Samuels and Trey Edmunds.
Marlon Mack, RB, Indianapolis Colts (hand) – Mack will miss another game as he recovers from a fractured hand he suffered in Week 11. He is targeting a Week 14 return and the Colts will continue to lean on Jonathan Williams and Nyheim Hines in the passing game. Williams has RB2 value this week against the Titans.
Damien Williams, RB, Kansas City Chiefs (ribs) – Williams was ruled out for Sunday’s matchup against the Raiders. He sustained a rib injury in Week 11 versus the Chargers and did not practice last week. The Chiefs will look to LeSean McCoy and Darrel Williams this week, both of whom have RB3/flex value.
Jordan Howard, RB, Philadelphia Eagles (shoulder) – Howard still has not been cleared for contact and was ruled out for Week 13 in Miami. The Eagles will continue to lean on rookie Miles Sanders, with Jay Ajayi and Boston Scott backing him up.
JuJu Smith-Schuster, WR, Pittsburgh Steelers (knee) – Despite clearing the concussion protocol, Smith-Schuster will miss his second game in a row with a knee issue. He was seen with a knee brace during the week and did not practice. James Washington and Diontae Johnson will be the main targets for quarterback Devlin Hodges against the Browns this week.
T.Y. Hilton, WR, Indianapolis Colts (calf) – Hilton suffered a setback during practice with the calf injury that kept him sidelined for three games and will miss Week 13 against the Titans. The oft-injured Colts wideout has only played in seven games this year. The team will continue to lean heavily on the run game, as well as Zach Pascal, Chester Rodgers and Marcus Johnson in three-wide sets.
Golden Tate, WR, New York Giants (concussion) – Tate did not practice all week while still in the protocol from a concussion sustained in last week’s loss to the Bears. Receivers Sterling Shepard and Darius Slayton should play big roles in the game, especially with tight end Evan Engram (foot) also ruled out. Cody Latimer should also see some targets against the Packers.
Dante Pettis, WR, San Francisco 49ers (knee) – Pettis was ruled out for Sunday’s game in what is shaping up to be one of the best games of the year in Baltimore. This should mean more targets for San Francisco wideouts Deebo Samuel and Emmanuel Sanders (ribs), who was left off of the final 49ers injury report.
Evan Engram, TE, New York Giants (foot) – Engram has not practiced since Week 9 and will miss yet another game with a foot sprain. Rhett Ellison (concussion) will also miss Week 13, leaving Kaden Smith and Scott Simonson to start at tight end for the Giants.
Gerald Everett, TE, Los Angeles Rams (knee) – Everett was ruled out for this week’s game in Arizona. He had been dealing with a wrist injury prior to this. Tyler Higbee should be the starter and has low-end TE1 value for Week 13.
David Njoku, TE, Cleveland Browns (wrist) – Njoku is inactive once again while the Browns’ coaching staff continues to work through the rehab for his wrist. It was unclear if this would be the week for Njoku amid earlier optimism. Demetrius Harris and Ricky Seals-Jones will start for the Browns at tight end. The two combined three targets in Week 12 against Miami.
Delanie Walker, TE, Tennessee Titans (ankle) – The Titans placed Walker on season-ending injured reserve this week after missing four games. Jonnu Smith will continue to start at tight end in place of the 35-year old veteran.
Rhett Ellison, TE, New York Giants (concussion) – Ellison still has not cleared the concussion protocol and has been ruled out for Sunday’s game against the Packers. Starter Evan Engram (foot) is also out.
Kyler Murray, QB, Arizona Cardinals (hamstring) – Murray is listed as questionable for Sunday’s game against the Rams due to a hamstring injury and is expected to play, per ESPN’s Adam Schefter. He practiced in full on Friday and has a great matchup this week against a Rams team that was just thrashed for 45 points against a mobile quarterback.
Drew Lock, QB, Denver Broncos (thumb) – Lock was activated from injured reserve on Friday and the determination was made that he will start in Week 13 against the Chargers. He took reps with the first team this week. This will be the rookie’s first NFL start, so without much to go on, it’s safe to assume he will not impact the fantasy value for pass catchers Courtland Sutton and Noah Fant.
Devlin Hodges, QB, Pittsburgh Steelers – Not injury related, but “Duck” Hodges will start this week against the Browns over Mason Rudolph. He took over for Rudolph in Week 12 and immediately connected with James Washington for a 79-yard touchdown. He should be the same, if not an upgrade, from Rudolph for the skill position players on the Steelers.
Derrick Henry, RB, Tennessee Titans (hamstring) – Henry did not appear on the Titans’ final injury report and is good to go in Indianapolis. Slot him in as a high-end RB1 this week.
Chris Thompson, RB, Washington Redskins (toe) – Thompson is expected to play in Week 13 at Carolina after a five-game absence with turf toe. He has lost almost all fantasy appeal, however, with Adrian Peterson and Derrius Guice taking over the Redskins’ backfield.
Tyreek Hill, WR, Kansas City Chiefs (hamstring) – Hill should be good to go Sunday against the Raiders after suffering a hamstring injury before the team’s Week 12 bye versus the Chargers. It was a minor strain, and Hill practiced in full on Friday. He’s right back in high-end WR1 territory this week.
Alshon Jeffery, WR, Philadelphia Eagles (ankle) – Jeffery was not on the Eagles’ final injury report after missing two games with an ankle injury. He was a late scratch last week, and comes back to a dream matchup in Miami. He will share targets with Nelson Agholor (knee), J.J. Arcega-Whiteside, Greg Ward and Mack Hollins.
Nelson Agholor, WR, Philadelphia Eagles (knee) – Agholor was also left off the Eagles’ final injury after missing Week 12 against the Seahawks and will suit up against the Dolphins. Consider him a dart throw with the competition for targets from Jeffery and Philadelphia’s other receivers, including Arcega-Whiteside, whom coach Doug Pederson said he wants to get more involved.
Mohamed Sanu, WR, New England Patriots (ankle) – Sanu is questionable coming into the Patriots’ Week 13 matchup in Houston and is expected to play. He missed Week 12 and along with Phillip Dorsett (concussion).
Phillip Dorsett, WR, New England Patriots (concussion) – Dorsett is also questionable for Sunday night’s game and is expected to play. Neither is an attractive Week 13 play, even against the leaky Houston defense. Hopefully you are not starting him or Sanu in your fantasy leagues.
George Kittle, TE, San Francisco 49ers (ankle) – Kittle was left off of the 49ers’ final injury report and will play on Sunday in Baltimore. He made a splash in Week 12 after a two-game absence and caught all six of his targets for 129 yards and a touchdown. When healthy, he is always a threat to finish as the week’s top tight end.
Matt Breida, RB, San Francisco 49ers (ankle) – Amid conflicting reports from both Ian Rapoport and Adam Schefter, it is unclear if the Niners running back will dress against the Ravens. Even if he does play for the first time in three games, he will likely be limited working behind Tevin Coleman and Raheem Mostert this week.
Adam Thielen, WR, Minnesota Vikings (hamstring) – Thielen is questionable going into Monday’s game in Seattle. He has been dealing with a hamstring injury since Week 7, but has been trending in the right direction after practicing all week. He has low-end flex value if he starts.
Zach Ertz, TE, Philadelphia Eagles (hamstring) – Ertz is going to be a game-time decision against the Dolphins this week while he is dealing with an injured hamstring. Ian Rapoport reports that Ertz is pushing to play, but as a precaution, the Eagles elevated Josh Perkins from the practice squad. The team also has Dallas Goedert, who was targeted eight times last week.
Luke Willson, TE, Seattle Seahawks (hamstring) – Willson is questionable going into Monday night’s matchup against the Vikings and will likely be a game-time decision. He has been absent since Week 10 and would assume a supporting role behind Jacob Hollister.